Nutritional biochemistry

Subject description

Metabolic (catabolic-anabolic) interrelationships in well-fed and starved states, under stress, trauma, body exercise; growing up; under cold conditions.

Digestion and absorption: digestive tract, digestion and absorption of proteins, digestion and absorption of carbohydrates, digestion and absorption of lipids; absorption physiology; biliary systems, urobilinogen cycle, enterohepatic circulation of bile acids, diet and cholesterol regulation of energy metabolism: the brain and energy metabolism; hormonic regulation of metabolism, alcohol and drugs, obesity.

Nutrigenomic and nutriomics, diet and health: effect of diet and drugs on atherosclerosis, diabetes, cardiovascular disease, diet and cancer.

Compounds of secondary metabolism: classification, distribution. Overview of their biosynthetic pathways with regulation. Importance of some secondary metabolites esp. isoprenoids (like carotenoids) and phenolic compounds (like anthocyanins and flavonoids) in human nutrition. Their potential biological activity. Bioavailability of phenolic compounds.

The subject is taught in programs

Objectives and competences

Educational outcomes: students will deepen their knowledge of the main metabolic processes of primary and secondary metabolisms, their regulation, function of selected tissues, organs and their metabolic pathways in different diseases.

Results: All the above should enable sStudents should be able to understand and connect complex processes of metabolism with proper diet.

Teaching and learning methods

Lectures. Seminars – team work and discussions.

Expected study results

Knowledge and understanding.

Basic sources and literature

  • T. Brody (1999). Nutritional Biochemistry, Academic Press, San Diego, ZDA, str. 57-128,133-153, 157-258, 273-307, 879-917
  • Biochemistry of Plant Secondary Metabolism. (2010). Ed. M. Wink..Wiley-Blackwell, Oxford, United Kingdom, str. 1-19, 92-116, 129-135, 182-193, 223-230, 258-278, 367-370.
  • D. S. Seigler. Plant Secondary Metabolism. (1998). Kluwer Academic Publishers, Boston, U.S.A., str. 486-500.
  • NUTRITIONAL BIOCHEMISTRY Current Topics in Nutrition Research (2015). Ed. C. Cox, CRC Press Taylor & Francis Group and Apple Academic Press, Inc., Oakville, Canada.

Revijalni članki s področja, tekoča periodika, druga učna gradiva…

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