Course description
Theories on the origins and development of life. Thermodynamics of biological systems. Basic chemistry of biological systems. Self-organiza-tion. Molecular genetics. Structure, growth, and division of biological cells. Cell membrane. Ener-gy conversions in biology. Biological regulation and homeostasis. Physiological systems in human. Structure, function and circulation of blood. Immune system. Flow of matter in biological systems. Population dynamics. Deterministic chaos and fractals in biology.
Course is carried out on study programme
2nd Cycle Postgraduate Study Programme in Electrical Engineering
Objectives and competences
To describe biological systems from an engineering perspective, analysis of the effects of electric currents and electromagnetic fields on biological systems.
Learning and teaching methods
The course will be guided through lectures in the class, individual study and laboratory work.
Intended learning outcomes
To integrate knowledge of the physiology of living organisms from the engineering point of view and to use engineering knowledge in solving biomedical problems.
Reference nosilca
JARM, Tomaž, ČEMAŽAR, Maja, MIKLAVČIČ, Damijan, SERŠA, Gregor. Antivascular effects of electrochemotherapy : implications in treatment of bleeding metastases. Expert review of anticancer therapy, 2010, vol. 10, no. 5, str. 729-746.
YARMUSH, Martin L., GOLBERG, Alexander, SERŠA, Gregor, KOTNIK, Tadej, MIKLAVČIČ, Damijan. Electroporation-based technologies for medicine: principles, applications, and challenges. Annual review of biomedical engineering, 2014, vol. 16, str. 295-320.
SERŠA, Gregor, TEISSIE, Justin, ČEMAŽAR, Maja, SIGNORI, Emanuella, KAMENŠEK, Urška, MARSHALL, Guillermo, MIKLAVČIČ, Damijan. Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer. Cancer immunology and immunotherapy, 2015, vol. 64, no. 10, str. 1315-1327.
ZOREC, Barbara, PRÉAT, Véronique, MIKLAVČIČ, Damijan, PAVŠELJ, Nataša. Active enhancement methods for intra- and transdermal drug delivery: a review. Zdravniški vestnik, 2013, letn. 82, št. 5, str. 339-356.
MALI, Barbara, JARM, Tomaž, SNOJ, Marko, SERŠA, Gregor, MIKLAVČIČ, Damijan. Antitumor effectiveness of electrochemotherapy: a systematic review and meta-analysis. European journal of surgical oncology, 2013, vol. 39, no. 1, str. 4-16.
KOTNIK, Tadej, PUCIHAR, Gorazd, MIKLAVČIČ, Damijan. Induced transmembrane voltage and its correlation with electroporation-mediated molecular transport. The journal of membrane biology, 2010, vol. 236, no. 1, str. 3-13.
KOTNIK, Tadej, KRAMAR, Peter, PUCIHAR, Gorazd, MIKLAVČIČ, Damijan, TAREK, Mounir. Cell membrane electroporation. Part 1, The phenomenon. IEEE electrical insulation magazine, 2012, vol. 28, no. 5, str. 14-23.
KOTNIK, Tadej. Lightning-triggered electroporation and electrofusion as possible contributors to natural horizontal gene transfer. Physics of life reviews, 2013, vol. 10, no. 3, str. 351-370.
YARMUSH, Martin L., GOLBERG, Alexander, SERŠA, Gregor, KOTNIK, Tadej, MIKLAVČIČ, Damijan. Electroporation-based technologies for medicine : principles, applications, and challenges. Annual review of biomedical engineering, 2014, vol. 16, str. 295-320.
KOTNIK, Tadej, FREY, Wolfgang, SACK, Martin, HABERL MEGLIČ, Saša, PETERKA, Matjaž, MIKLAVČIČ, Damijan. Electroporation-based applications in biotechnology. Trends in biotechnology, 2015, vol. 33, no. 8, str. 480-488.
Study materials
Tadej Kotnik, Damijan Miklavčič. Biološki sistemi, 2. izdaja. 2016, Založba FE, Ljubljana