Course description
Structure of the neuron, Nernst equation, transmembrane potential, the formation of an action potential, transmission of signals along the neurons and between neurons, synapses, neurotransmitters and their receptors. The idea of formal neuron and the basic neural networks. Muscles and specialities of skeletal, smooth and cardiac muscle. Hill’s equation, the process of muscle fatigue. Movement and its control: the lower motor neuron, upper motor neuron, the role of the brainstem, cerebellum, deeper brain structures and motor cortex. Receptors and sensory organs: the formation and shape of the signal, which is a result of perception; vision, hearing, pain and detection of chemical substances. Reflexes. Higher brain functions, memory, learning, sensory-motor integration. Electrotechnical devices that replace lost body functions.
Course is carried out on study programme
2nd Cycle Postgraduate Study Programme in Electrical Engineering
Objectives and competences
To introduce the students with the activity of living organisms and their components. The focus of the course is in understanding the ways of acquiring various information from the environment, transferring information in the organism, information processing, integration different types of information and producing appropriate response to this information. Physiology of a living organism is represented by an engineering point of view. This concept allows the student the transfer of optimized solutions from the nature to the technical environment (bionics) or design of the new facilities that are appropriate for compensation of lost body functions.
Learning and teaching methods
The course will be guided through lectures in the class, individual study and laboratory work.
Intended learning outcomes
To integrate knowledge of the physiology of living organisms from the engineering point of view and to use engineering knowledge in solving biomedical problems.
Reference nosilca
- MALI, Barbara, ZULJ, Sara, MAGJAREVIĆ, Ratko, MIKLAVČIČ, Damijan, JARM, Tomaž. Matlab-based tool for ECG and HRV analysis. Biomedical signal processing and control, 2014, vol. 10, str. 108-116.
- MALI, Barbara, MIKLAVČIČ, Damijan, SERŠA, Gregor, JARM, Tomaž. Comparison of protocols for synchronized electroporation pulse delivery. V: 6th European Conference of the International Federation for Medical and Biological Engineering, MBEC 2014, 7-11 September 2014, Dubrovnik, Croatia. LACKOVIĆ, Igor (ur.), VASIĆ, Darko (ur.). IFMBE proceedings, (IFMBE proceedings, ISSN 1680-0737, vol. 45). Cham [etc.]: Springer, cop. 2014, str. 586-589, ilustr.
- MALI, Barbara, JARM, Tomaž, ČOROVIĆ, Selma, PAULIN-KOŠIR, Marija Snežna, ČEMAŽAR, Maja, SERŠA, Gregor, MIKLAVČIČ, Damijan. The effect of electroporation pulses on functioning of the heart. Medical & biological engineering & computing, 2008, vol. 46, no. 8, str. 745-757.
- ŽUPANIČ, Anže, RIBARIČ, Samo, MIKLAVČIČ, Damijan. Increasing the repetition frequency of electric pulse delivery reduces unpleasant sensations that occur in electrochemotherapy. Neoplasma, 2007, vol. 54, 3, str. 246-250.
- MIKLAVČIČ, Damijan, PUCIHAR, Gorazd, PAVLOVEC, Miran, RIBARIČ, Samo, MALI, Marko, MAČEK LEBAR, Alenka, PETKOVŠEK, Marko, NASTRAN, Janez, KRANJC, Simona, ČEMAŽAR, Maja, SERŠA, Gregor. The effect of high frequncy electric pulses on muscle contractions and antitumor efficiency in vivo for a potential use in clinical electrochemotherapy. Bioelectrochemistry, 2005, vol. 65, no. 2, str. 121-128.
Study materials
- Purves D, Augustine GJ, Fitzpatrick D, Hall WC, LaMantia AS, McNamara JO, White LE. Neuroscience. Sinauer Associates; 4th Edition edition, 2007.
- Deutsch S, Deutsch A. Understanding the nervous system An engineering perspective. Wiley-IEEE Press, 1993.
- Pflanzer RG. Experimental and Applied Physiology. McGraw-Hill, 2007.
- Guyton AC, Hall JE. Textbook Of Medical Physiology. W.B. Saunders Company: 10th ed. 2000.
- Barth FG, Humphrey JAC, Secomb TW. Sensors and sensing in biology and enginnering. Springer, 2003.